《儿科学》全册配套教学课件Mucocutaneous lymph node syndrome (MCLS)• Kawasaki disease (KD)• First described in Japan in 1967• Definition: An acute febrile vasculitis ( the medium, small-sized arteries , especially coronary artery)• Become the most important posteriority cardiac disease in childhood• Male-to-female ration 1.5:1• Average age 1.5 yrs, 80%<5 yrsEtiology and pathogenesis1. 感染因素 infected factors• 区域流行特性• 明显的季节性• 疾病自限性• 高发于婴幼儿而成人罕见• 病原：自然界普遍存在的微生物• 大多数个体无症状感染，成人期获得性免疫细菌或病毒毒素触发因素超抗原全身性血管炎，冠状动...
